International Header

BMC Port of Springer Nature: Effect of interventions to reduce malaria incidence among military personnel on active duty

Effect of interventions to reduce malaria incidence among military personnel on active duty

BMC Port of Springer Nature: Effect of interventions to reduce malaria incidence among military personnel on active duty

Last updated:
नवम्बर 22/2021
|  5 min read

BMC Port of Springer Nature: Effect of interventions to reduce malaria incidence among military personnel on active duty

BMC Port of Springer Nature: Effect of interventions to reduce malaria incidence among military personnel on active duty

YouTube video highlight

Effect of interventions to reduce malaria incidence among military personnel on active duty

Read more about the project

BMC Port of Springer Nature: Effect of interventions to reduce malaria incidence among military personnel on active duty

Thumbnail Slider Image
कोई आइटम नहीं मिला.

Effect of interventions to reduce malaria incidence among military personnel on active duty: study protocol for a cluster randomised controlled trial of the impact of etofenprox-treated uniforms, permethrin-treated uniforms and DEET insect repellent.

Background

While there is strong evidence that bite protection methods such as permethrin-treated clothing and topical insect repellents are protective against insect bites, there are few studies assessing the impact on malaria infection. This study will estimate the protective efficacy of treated uniforms and DEET insect repellent on the incidence of malaria infection among military personnel in an operational setting. Permethrin-treated uniforms used with DEET lotion will be compared to etofenprox-treated uniforms with DEET lotion. The effect of DEET lotion will be estimated by comparing permethrin-treated uniforms with DEET or placebo lotion.

Method

A cluster randomised double-blind placebo-controlled trial is planned to evaluate the effectiveness of the interventions on preventing malaria infections in soldiers on active duty at Mgambo National Service Camp in Tanga, Tanzania. The arms are (1) permethrin-treated uniform with 30% DEET liposome formula; (2) permethrin-treated uniform with placebo lotion; (3) candidate insect repellent system, i.e. etofenprox-treated uniform with 30% DEET liposome formula; and (4) placebo, i.e. untreated uniforms with placebo lotion. The primary outcome is the incidence of Plasmodium falciparum malaria infection detected by polymerase chain reaction (PCR) by active case detection using surveys every 2 weeks for 12 months. Rapid diagnostic tests will be used for the diagnosis of participants with symptoms.

The unit of randomisation will be combania: companies formed by recruits aged 18 to 25 years; combania do activities together and sleep in the same dormitory. Unequal randomisation will be used to optimise statistical power for the primary comparison between permethrin-treated uniforms with DEET and etofenprox-treated uniforms with DEET.

Discussion

This trial will provide the estimate of the effects of permethrin with DEET compared to those of the new fabric treatment etofenprox with DEET and any additional effect of using DEET. The results will inform strategies to protect military personnel and civilians who have more outdoor or occupational malaria exposure than the general public.

You can find the study written by Daniel Msellemu, Amanda Ross, Lucky Temu, Irene Moshi, Lorenz Hofer, Charles Mwanziva, Yadon M. Kohi & Sarah J. Moore here.

BMC Port of Springer Nature: Effect of interventions to reduce malaria incidence among military personnel on active duty

Effect of interventions to reduce malaria incidence among military personnel on active duty: study protocol for a cluster randomised controlled trial of the impact of etofenprox-treated uniforms, permethrin-treated uniforms and DEET insect repellent.

Background

While there is strong evidence that bite protection methods such as permethrin-treated clothing and topical insect repellents are protective against insect bites, there are few studies assessing the impact on malaria infection. This study will estimate the protective efficacy of treated uniforms and DEET insect repellent on the incidence of malaria infection among military personnel in an operational setting. Permethrin-treated uniforms used with DEET lotion will be compared to etofenprox-treated uniforms with DEET lotion. The effect of DEET lotion will be estimated by comparing permethrin-treated uniforms with DEET or placebo lotion.

Method

A cluster randomised double-blind placebo-controlled trial is planned to evaluate the effectiveness of the interventions on preventing malaria infections in soldiers on active duty at Mgambo National Service Camp in Tanga, Tanzania. The arms are (1) permethrin-treated uniform with 30% DEET liposome formula; (2) permethrin-treated uniform with placebo lotion; (3) candidate insect repellent system, i.e. etofenprox-treated uniform with 30% DEET liposome formula; and (4) placebo, i.e. untreated uniforms with placebo lotion. The primary outcome is the incidence of Plasmodium falciparum malaria infection detected by polymerase chain reaction (PCR) by active case detection using surveys every 2 weeks for 12 months. Rapid diagnostic tests will be used for the diagnosis of participants with symptoms.

The unit of randomisation will be combania: companies formed by recruits aged 18 to 25 years; combania do activities together and sleep in the same dormitory. Unequal randomisation will be used to optimise statistical power for the primary comparison between permethrin-treated uniforms with DEET and etofenprox-treated uniforms with DEET.

Discussion

This trial will provide the estimate of the effects of permethrin with DEET compared to those of the new fabric treatment etofenprox with DEET and any additional effect of using DEET. The results will inform strategies to protect military personnel and civilians who have more outdoor or occupational malaria exposure than the general public.

You can find the study written by Daniel Msellemu, Amanda Ross, Lucky Temu, Irene Moshi, Lorenz Hofer, Charles Mwanziva, Yadon M. Kohi & Sarah J. Moore here.

फोटो थंबनेल ब्लॉग लेखक
Media Mentions from BMC
BMC
A pioneer of sustainable open access, where research is always in progress.
मीडिया मेंशन

BMC Port of Springer Nature: Effect of interventions to reduce malaria incidence among military personnel on active duty

Effect of interventions to reduce malaria incidence among military personnel on active duty: study protocol for a cluster randomised controlled trial of the impact of etofenprox-treated uniforms, permethrin-treated uniforms and DEET insect repellent.

Background

While there is strong evidence that bite protection methods such as permethrin-treated clothing and topical insect repellents are protective against insect bites, there are few studies assessing the impact on malaria infection. This study will estimate the protective efficacy of treated uniforms and DEET insect repellent on the incidence of malaria infection among military personnel in an operational setting. Permethrin-treated uniforms used with DEET lotion will be compared to etofenprox-treated uniforms with DEET lotion. The effect of DEET lotion will be estimated by comparing permethrin-treated uniforms with DEET or placebo lotion.

Method

A cluster randomised double-blind placebo-controlled trial is planned to evaluate the effectiveness of the interventions on preventing malaria infections in soldiers on active duty at Mgambo National Service Camp in Tanga, Tanzania. The arms are (1) permethrin-treated uniform with 30% DEET liposome formula; (2) permethrin-treated uniform with placebo lotion; (3) candidate insect repellent system, i.e. etofenprox-treated uniform with 30% DEET liposome formula; and (4) placebo, i.e. untreated uniforms with placebo lotion. The primary outcome is the incidence of Plasmodium falciparum malaria infection detected by polymerase chain reaction (PCR) by active case detection using surveys every 2 weeks for 12 months. Rapid diagnostic tests will be used for the diagnosis of participants with symptoms.

The unit of randomisation will be combania: companies formed by recruits aged 18 to 25 years; combania do activities together and sleep in the same dormitory. Unequal randomisation will be used to optimise statistical power for the primary comparison between permethrin-treated uniforms with DEET and etofenprox-treated uniforms with DEET.

Discussion

This trial will provide the estimate of the effects of permethrin with DEET compared to those of the new fabric treatment etofenprox with DEET and any additional effect of using DEET. The results will inform strategies to protect military personnel and civilians who have more outdoor or occupational malaria exposure than the general public.

You can find the study written by Daniel Msellemu, Amanda Ross, Lucky Temu, Irene Moshi, Lorenz Hofer, Charles Mwanziva, Yadon M. Kohi & Sarah J. Moore here.

फोटो थंबनेल ब्लॉग लेखक
Media Mentions from BMC
BMC
A pioneer of sustainable open access, where research is always in progress.
मीडिया मेंशन
browse all articles
यहाँ सॉयर में
Halfway Anywhere: Continental Divide Trail Gear Guide (2025 Survey)
Read More

मीडिया मेंशन

Babies carried in treated wraps were about two-thirds, or 66 per cent, less likely to develop the disease.

Maeve Cullinan
Global Health Security Reporter

मीडिया मेंशन

This particular formula is nongreasy, nonsticky, and lacks a strong odor, making it highly appealing for direct skin application.

Jill Di Donato
लेखक

मीडिया मेंशन

The best filter, I took care to sleep with it on cold nights and back-flushed her in town.

Lauren “Mothra” Mullen
Hiker, Writer
<<  Previous Post
No previous post!
Check out our Directory
Next Post  >>
No next post!
Check out our Directory