डोमिनिकन गणराज्य में घरों और स्कूलों में पॉइंट-ऑफ-यूज़ वॉटर फिल्टर के यादृच्छिक, नियंत्रित संभावित परीक्षण में दस्त का प्रसार

Background

स्वच्छ पेयजल तक स्थायी पहुंच का अभाव सर्वोपरि वैश्विक महत्व का मुद्दा बना हुआ है, जिससे सालाना लाखों लोगों की मौत हो जाती है। स्वच्छ पेयजल तक स्थायी पहुंच प्रदान करने के लिए सर्वोत्तम प्रथाएं, हालांकि, अस्पष्ट बनी हुई हैं। कम लागत वाली, घर में, उपयोग जल निस्पंदन सिस्टम की व्यापक स्थापना एक आशाजनक रणनीति है।

Methods

We conducted a prospective, randomized, controlled trial whereby 16 villages were selected and randomly assigned to one of four treatment arms based on the installation location of Sawyer® PointONE™ filters (filter in both home and school; filter in home only; filter in school only; control group). Water samples and self-reported information on diarrhea were collected at multiple times throughout the study.

Results

Self-reported household prevalence of diarrhea decreased from 25.6 to 9.76% from installation to follow-up (at least 7 days, and up to 200 days post-filter installation). These declines were also observed in diarrhea with economic or educational consequences (diarrhea which led to medical treatment and/or missing school or work) with baseline prevalence of 9.64% declining to 1.57%. Decreases in diarrhea prevalence were observed across age groups. There was no evidence of a loss of efficacy of filters up to 200 days post-filter installation. Installation of filters in schools was not associated with decreases in diarrhea prevalence in school-aged children or family members. Unfiltered water samples both at schools and homes contained potential waterborne bacterial pathogens, dissolved heavy metals and metals associated with particulates. All dissolved metals were detected at levels below World Health Organization action guidelines.

निष्कर्ष

This controlled trial provides strong evidence of the effectiveness of point-of-use, hollow fiber membrane filters at reducing diarrhea from bacterial sources up to 200 days post-installation when installed in homes. No statistically significant reduction in diarrhea was found when filters were installed in schools. Further research is needed in order to explore filter efficacy and utilization after 200 days post-installation.

Trial registration

ClinicalTrials.gov, NCT03972618. Registered 3 June 2019—retrospectively registered.

Tintle, N., Van De Griend, K., Ulrich, R. et al. Diarrhea prevalence in a randomized, controlled prospective trial of point-of-use water filters in homes and schools in the Dominican Republic. Trop Med Health 49, 1 (2021). https://doi.org/10.1186/s41182-020-00291-y

To find the complete study, head here.